Active Biotech provides update on laquinimod in Huntington’s disease
Lund Sweden, July 31, 2018 –Active Biotech (NASDAQ OMX NORDIC: ACTI) today provided an update regarding the clinical development of laquinimod by Teva Pharmaceutical Industries Ltd. The Phase 2 LEGATO-HD trial evaluating the safety and efficacy of laquinimod as a treatment in Huntington’s disease (HD) did not meet its primary endpoint of change from baseline after 12 months of treatment, as measured by the Unified Huntington’s Disease Rating Scale – Total Motor Score (UHDRS-TMS). The study’s secondary endpoint, reduction of brain atrophy (measured by caudate volume) was met. The safety results were similar to the expected event profile in this patient population.