Tasquinimod

Laquinimod

Naptumomab Estafenatox

Project Overview

Active Biotech focuses on the research and development of pharmaceuticals in therapeutic areas such as cancer and inflammatory diseases with unmet medical need. The project portfolio comprises small, orally active immunomodulatory molecules as well as antibody-based immunotherapy.

Therapeutic areas of high medical need

Pipeline

Disease Area
Discovery
Preclinical
Phase I
Phase II
Phase III
Partner
Hematological malignancies
Tasquinimod Multiple myeloma*
Tasquinimod Myelofibrosis**
Tasquinimod Myelofibrosis
Inflammatory eye disorders
Laquinimod eye drops, safety and tolerability
Laquinimod eye drops, ocular biodistribution
Solid tumors
Naptumomab Combination with docetaxel in non-small cell lung cancer
Naptumomab Combination with anti-PDL1 (durvalumab) in solid tumors
Study ongoing
* In an academic partnership with the Abramson Cancer Center, Philadelphia, University of Pennsylvania
** Study preparations ongoing