Whole-Body Autoradiography Services
Quantitative whole-body autoradiography (WBA) is recognized as a comprehensive assessment of the distribution of radio labeled drugs, thereby answering specific pharmacokinetic issues regarding e.g. tissue distribution, tissue, such as tumor, uptake and routes of elimination.
Quantitative WBA can also be used for dosimetric calculations prior to studies with radio labeled compounds administered to humans.
The visual representation, the autoradiogram, reveals the presence and localization of the radio label in specific tissues. The use of digital image processing and radio labeled standards supports the qualitative and quantitative analysis of individual whole-body sections. Phosphor imaging has added significant increase in sensitivity as well as turnover time to the technology.